Colossal Dire Wolf Tech Named a TIME Best Invention

TIME 2025 honors Colossal’s EPC blood-draw cloning for conservation.

BY Jeffrey Kluger

TIME has selected Colossal Biosciences’ non-invasive blood-draw cloning for its Best Inventions of 2025 list. The method uses endothelial progenitor cells (EPCs) collected via a simple blood draw—hardier, faster-dividing cells that reduce stress on donor animals and streamline cloning for conservation programs. The recognition highlights how platform tools developed around the colossal dire wolf effort translate into practical, humane approaches that bank genetic diversity and support threatened species. As biodiversity loss accelerates, EPC cloning offers wildlife programs a scalable way to safeguard genetic lines without surgical biopsies.

Full feature on Time.