De-Extinction

[ DISRUPTIVE CONSERVATION & PRESERVATION ]
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EXTINCTION IS A COLOSSAL PROBLEM FACING THE WORLD.

And Colossal is the company that’s going to fix it.

Combining the science of genetics with the business of discovery, we endeavor to jumpstart nature’s ancestral heartbeat. To see the Woolly Mammoth thunder upon the tundra once again. To advance the economies of biology and healing through genetics. To make humanity more human. And to reawaken the lost wilds of Earth. So we, and our planet, can breathe easier.

DATA SUBSET 009
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Colossal Labs & Systems
De-Extinction
  • We are the
    de-extinction company.
  • We accept the challenge.
  • On behalf of humanity, the animal kingdom and the universe at large.

A LOOK
AT EXTINCTION
TODAY.

Extinction, as it pertains to biology, is defined as “the dying out or extermination of a species.” This can be caused by a number of factors such as natural disasters, planetary shifts, movements of the sun and stars, human causation or evolution itself.

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HUMAN CAUSATION

Of all the root causes of modern extinction, the most concerning and hyperactive factor is that of human causation. Notably, causation from the advent of human civilization and industry. This alone has created a destructive force - within only the last 200 to 300 hundred years - that is accelerating extinction at a pace unimaginable across the entire 4.5 billion year history of Planet Earth.

Evolution as we know it moves incredibly slowly. Massive natural disasters, like a volcanic event or asteroid collision that theoretically claimed the dinosaurs, are extremely rare. This is evidenced through analysis of sedimentary rock and other geological metrics.

For extinction to suddenly skyrocket, there has to be some other force at play. Judging by measurements of carbon in the atmosphere, destruction of ecosystems, pollution, overfishing and hunting, and more, the root cause is identifiably that of human causation. So while the last few centuries have been a boon to the human populace, the rest of Earth’s species, both flora and fauna, are paying the price as a result. At a speed that our planet and all of its inhabitants are quite simply not prepared for.

The loss of species at its natural, evolutionary speed is difficult to define as detrimental. In many ways, the Earth is in control of this process - systematically replacing a defunct species with a more efficient one. This takes millions of years for each instance to occur. In contrast, the loss of species due to human causation is entirely not natural. The loss and its effects are both rapid and dramatic. Because when a species goes extinct due to external human-related factors, there is more than just a loss of a natural gift or a page in a biology text.

Rather, when a species is forcibly removed from existence due to pollutive or aggressive human interference, the loss is more accurately described as the elimination of a key balancing factor within a given delicate ecosystem. Every plant and animal, whether predator or prey, plays a critical role in the sustainability of our planet’s survival systems. When one is removed the entire chain suffers. Research from top scientists, biologists and geologists from around the world is starting to paint the picture in real, hard data. The numbers are staggering.

30,000

species per year on average are being driven to extinction.

6

Per hour

150

Per day

Up To
55,000

Per year

50%
The World Animal Foundation predicts that up to
ONE-HALF OF ALL SPECIES

could become extinct by 2050.

Panda.org Estimates

That the rate of extinction in 2021 is 10,000 times faster because of human activity.

IN TOTAL
36%

Terrestrial species
declined 36%

81%

81% of freshwater
species disappeared

36%

Marine species
vanished by 36%

All between 1970 and 2012 alone.
 

The UN has declared that

1,000,000
animal and plant
species are threatened
with extinction.
Since 1990, native
species of most land
habitats have FALLEN 20%.
At least
680 VERTEBRATE
SPECIES
have been driven to extinction
since the 16th century.
MORE THAN
40%

of amphibians

33%

of reef-forming corals

and more than 1/3
of all marine mammals
are THREATENED.

The International Union for Conservation of Nature (IUCN) estimates

IUCN Estimates
38%
OF ALL SPECIES

are on the verge of extinction today.

68%
OF PLANT SPECIES

studied by the IUCN are on the brink of extinction.

Almost
50%
OF ALL PRIMATE SPECIES

are at risk of extinction.

Equally HALF of the globe’s 5,491
mammal species are in decline -

20% in danger of complete extinction.

Experts at Earth.org summarize the current loss of species as a MASS EXTINCTION EVENT that is actively underway.
500
MILLION YEARS
 

The IUCN identifies habitat loss as a main threat to 85% OF ALL SPECIES on the Red List.

Panda.org estimates that

50%

OF THE WORLD’S
ORIGINAL FORESTS
Have disappeared.

At a rate

10 TImeS

HIGHER than
possible
regrowth.

BiologicalDiversity.org states

40%

OF EARTH’S LAND is consumed by human food production.

Up from ONLY
7% in 1700

50%

OF EARTH’S TOTAL LAND MASS has been transformed for human use.

The Intergovernmental
Panel on Climate
Change reports

concentrations in the atmosphere are higher than at anytime in the last

650,000 YEARS.

The problem is beyond massive. The problem is a human one. And the solution is a human one, too. The science of de-extinction.

George Church, Ph.D.
Co-Founder

De-Extinction

At Colossal, George Church, Ph.D. and a team of world-renowned genetic scientists, are currently pioneering a practical, working model of de-extinction. The team operates at the leading edge of genetic engineering and restorative biology and are currently working on Colossal’s launch project:

Bringing Back the
Woolly MAMMOTH
WITHIN THE NEXT
5 YEARS.

THE MAMMOTH REPRESENTS THE BEGINNINGS OF
DE-EXTINCTION.

Starting with the genetic resurrection of the Woolly Mammoth, the goal of Colossal will be to develop a de-extinction library of animals as well as housing genetic DNA/embryos from endangered animals. This process will slow the long term impacts of human-induced loss of biodiversity and give threatened species a buffer against outright extinction as numbers dwindle.

Today our laboratory employs a team of scientists who understand and are experienced, world-class authorities in the applications and advancements of CRISPR genome editing, and developing software and other tools for the purposes of:

  • +Endangered Animal Back Up
  • +De-Extinction
  • +Species Diversification
  • +Species Replacement
  • +Species Conservation

The results from our lab will directly address issues related to loss in biodiversity and overall species counts resulting from the human-accelerated degradation of land, sea and air. Ultimately, the aim is to reverse this damage by reintroducing critical animal and plant species that played active roles in the preservation of some of Earth’s most climate-beneficial ecosystems. Many of which have all but vanished entirely today.

[ QUOTE ]

“We have a duty to heal our planet, and to sustain it for future generations. With creativity, caution, and consultation, ethical use of modern genetic technologies can help stabilize ecosystems while bringing the animals and plants who share our planet back from the brink of extinction.”

ALTA CHARO

Juris Doctor, Warren P. Knowles Professor of Law and
Bioethics, leading American authority on Bioethics

[ Colossal Scientific Advisory Board Member ]

DE-EXTINCTION IS A SCIENCE THAT’S CONCERNED NOT ONLY WITH TOMORROW, BUT ALSO WITH 20 YEARS, 300 YEARS, 5,000 YEARS FROM NOW.

Conserve & Protect :

Rewilding

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The science of de-extinction finds peak application through the processes of reintroduction and revitalization - known as rewilding. The concept is simple: return extinct animals to their original habitats so they can begin reversing the detrimental effects of climate damage. Thus, by leveraging genetic engineering, Colossal will be able to rewild vital landscapes, ending the threat of extinction faced by many species currently in existence, having a positive net effect on carbon offset, and supporting the local economies dependent on the targeted, affected habitats.

In the case of the cold-tolerant elephant mammoth hybrid specifically, rewilding equates to the reintroduction of a large cold-tolerant mammal grazer to the tundra regions of the Earth. By stirring up the ice-locked surfaces of the landscape, stomping out thin, low-oxygen trees, and exposing healthy, carbon-trapping grasses, Mammoth populations will begin immediately restoring the tundra’s role as a climate protector and balancer of greenhouse gases.

 

Beyond the Mammoth :

EXTINCTION REVERSAL & SPECIES PRESERVATION

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Colossal will revolutionize biological history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species. On the journey we will build radical new software tools and technologies to transform genomics from an experimental state into an active, practical, reliable and efficient science.

 
De-Extinction
Knowledge
Bank
CRIPSR / CAS9 TECHNOLOGY
Research & Development
CONTENT DOWNLOADS

Downloadable PDF’s

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Below are PDFs containing the latest research and developments in the field of de-extinction.

Conserve & Protect :

de-extinction

RESOURCE LINKS

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Below are links to website resources containing the latest research and developments in the field of de-extinction.

Mammuthus Primigenius

MEET
THE WOOLLY
MAMMOTH.

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Earth’s old friend and new hero.

DE-EXTINCTION OF THE WOOLLY MAMMOTH

De-extinction of the Woolly Mammoth is truly a Colossal mission. So, how exactly are we getting there?

Discover the details
in our Science & Technologies
section
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