At Colossal Biosciences, we endeavor to jumpstart nature’s ancestral heartbeat. To see the Woolly Mammoth thunder upon the tundra once again. To advance the economies of biology and nutrition. To make humanity more human. And to reawaken the lost wilds of Earth. So we, and our planet, can breathe easier.
These things, which were not achievable before, are now. In our laboratories. Through our breakthroughs in CRISPR and genetic engineering.
We are leading the new charge of bioscience. We accept the responsibility. And we can see the light at the end of it all.
Many companies claim they're going to change the world.
At Colossal, we believe that the world doesn't need to be changed.
Which is exactly what we're doing through purposeful advancements in science. Because when it comes to our planet, science is everything.
“In 2014, I asked my friend Elon Musk who he knew who was poised to make profound changes in the field of genomics, and he said: George Church.
So in June 2014, I visited George at his lab in Boston. I immediately knew I’d be looking for an opportunity to collaborate with George. Global Space Ventures is excited to be backing Colossal. George Church’s personal passion for the mission, combined with the stellar team assembled by serial entrepreneur Ben Lamm, is at the perfect intersection of audacious yet achievable. The path to de-extinction is now at hand, and leveraging CRISPR/Cas9 technology, to bring back extinct species and preserve those that we have, will have profound importance to humanity.”
Through technological and engineering breakthroughs in biosciences and genetics, Colossal is accepting humanity’s duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition.
Colossal will revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species. On the journey we will build radical new software tools and technologies to advance the science of genomics overall.
"I've followed the ground-breaking work of George Church for years. I have also invested in and coached Ben Lamm when he founded Hypergiant. These two are a powerhouse team who have the ability to completely shift our understanding of modern genetics while developing innovative technologies that not only help bring back lost species, but advance the entire industry. I am proud to be an investor in their journey."
World Famous Life-Coach, Author,
Investor and Entrepreneur
[ colossal investor ]
As grateful citizens of the universe, we recognize the value of habitable environments for our species and those around us. As tenants of Earth, currently the only livable planet in our solar system, it is not enough just to be grateful, but we must also be active in a role as custodians and defenders of the nature which sustains life.
Balance is not for us to determine. It has been refined for billions and billions of years by forces such as gravity, geology and evolution. Thus it is not our role to pick and choose the winners and losers. But merely to respect all living things - past and present.
Today, the Woolly Mammoth. But tomorrow, maybe the cure for blindness, eradication of tumors and elimination of disease. The potential of bioscience is almost unlimited, and we are at the forefront, pushing the boundaries.
At Colossal we are driven by the forces of virtue and moral good - working for a healthier planet, a healthier human populace and a pursuit of that which we recognize as goodness, compassion and honest, pure science.
Colossal expands the boundaries of what is possible with CRISPR and other cutting edge biological engineering technologies, always with a commitment to responsible science and stewardship of our planet’s natural diversity. We are guided by these values:
[ Unbreakable PRINCIPLES ]
"Healing our Earth's ecosystems is of critical planetary importance.
The overwhelming success of the human species has come at a profound price, the massive global loss of biodiversity and destruction of basic ecological services that have been tuned over millions of years to support life. Colossal is pioneering an approach to ecosystem restoration and bioscience innovation that can help reverse this trend, restoring some balance to the world."
Managing Partner JAZZ Ventures, founder & CEO of NeuroInsights, best-selling author, founder of Neurotechnology Industry Organization, creator of Experiential Technology and NeuroGaming Conference and Expo
[ Colossal Investor ]
It will be up to humans to reverse the harm caused by humans. Hence, our team is intentionally selected to accomplish exactly that - comprised of world-leaders in science and genetics to ecology and industry.
Ben Lamm is the co-founder and CEO of Colossal. Ben is a serial technology entrepreneur driven to solve the most complex challenges facing our planet. For over a decade, Ben has built disruptive businesses that future-proof our world. In addition to leading and growing his own companies, he is passionate about emerging technology, science, space and climate change. Active in angel investing, incubators and startup communities, Ben invests in software and emerging tech, and is deeply engaged in the technology, defense and climate change communities.
Prior to Colossal, Ben served as the founder and CEO to a number of companies, including Hypergiant, an enterprise AI software company focused on critical infrastructures, space, and defense; Conversable, the leading conversational intelligence platform that helps brands reach customers through automated experiences acquired by LivePerson; and Chaotic Moon, a global creative technology powerhouse acquired by Accenture. Ben was also the co-founder of Team Chaos, a consumer gaming company acquired by Zynga.
Ben is a fellow of the Explorer’s Club, whose mission is to promote the scientific exploration of land, sea, air, and space by supporting research and education in the physical, natural and biological sciences. He also serves as a Scientific Advisory Board member on the Planetary Society and sits on the Advisory Board for the Arch Mission. Ben has appeared as a thought leader in many publications, including the Wall Street Journal, New York Times, Forbes, Entrepreneur, Wired, TechCrunch, VentureBeat, and Newsweek on topics such as innovation, technology and entrepreneurship.
George Church, Ph.D. acts as the co-founder and lead genetics advisor for Colossal. He is a professor at Harvard and MIT, runs the Church lab at the Harvard Medical School, and is a Core Faculty member of the Wyss Institute at Harvard where he leads the Synthetic Biology Platform. Church is a recognized leader in genomics, having pioneered a number of advances and breakthroughs that have helped advance the entire field.
In 1984 with Wally Gilbert, Church developed the first direct genomic sequencing method and barcode-multiplexing tags. This led to automation and software used for the first cellular genome sequence (Helicobacter) in 1994, which evolved into ‘in-situ sequencing’ (1999) and ‘next-generation sequencing’ (2014).
Church then pioneered chip-based DNA libraries, genome editing, and stem cell engineering. He also pioneered new privacy, biosafety, human engineering, environmental, biosecurity, and bioethics strategies and training. Today, he and his group champion open-access human genome data.
For his achievements and direct contributions to genomics and the sciences as a whole, Church has received numerous awards. Some of his most prestigious recognitions include National Academy of Sciences, National Academy of Engineering, the Heptannual Bower Award, and Prize for Achievement in Science from the Franklin Institute.
Over the past 25 years, Andrew Busey has pioneered some of the internet industry’s most important technologies – including work on Mosaic, the first web browser (now part of Microsoft Internet Explorer); creating iChat, the first web based chat system and one of the first instant messaging applications; building WebCenter, the first web-based customer service technology (now part of Avaya); creating a new class of asynchronous games (Challenge Games, acquired by Zynga); and innovating in conversational commerce (Conversable, acquired by LivePerson). He is the primary inventor on twenty-nine patents.
Andrew is an active angel investor in companies such as Aceable, Cratejoy, FlashParking, ZenBusiness, and Waterloo Water. He is the author of Accidental Gods, a novel about a group of scientists who simulate a universe where life develops, and Secrets of the MUD Wizards, the first book about developing multiplayer games.
He has a degree in computer science from Duke University and an MBA from The Wharton School at the University of Pennsylvania.
Eriona Hysolli, Ph.D., is the Head of Biological Sciences at Colossal. Previously, she was a postdoctoral fellow in the laboratory of George Church, PhD., Harvard Medical School from 2015 – 2021, where she focused on developing and optimizing novel genetic tools for multiplex mammalian genome engineering including mammoth de-extinction and building a virus-resistance human cell line. Eriona graduated summa cum laude from Rutgers University with a double major in Neuroscience and German and a minor in Chemistry, then pursued graduate research at Yale University. At Yale, she studied the gene expression changes as human somatic cells transition to human embryonic stem-cell like cells (iPSCs) that hold great potential in health and medicine. Eriona also studied how microRNAs modulate this process through epigenetic changes.
Eriona’s authored publications include characterizing different populations of human iPSCs arising during reprogramming, setting up a human cell-bacteria co-culture model to study how biocontainment can be exploited for probiotic development, and mutliplex editing of TAG to TAA codons genome-wide in human cells. Unpublished work includes engineering mammoth traits in elephant cells, comprehensively characterizing via computational analysis all DNA changes that make mammoths different from extant elephants, and visualizing ancient DNA in situ.
Kent Wakeford is a leader in the technology industry with over twenty years of experience in digital consumer products and data measurement. Kent serves on the board of Skillz [NYSE SKLZ] which is a leading mobile platform with over 100 million users around the world.
Kent is the co-founder and Vice Chairman of Gen.G Esports which, according to Forbes, is the one most valuable esports team organization in the world.
Prior, Kent was Chief Operating Officer of Kabam, where he helped grow Kabam to a globally diverse company with over 1,000 employees in 7 countries and games that were played by over 500 million people around the world. Kent helped lead the sale of Kabam to Netmarble Games for $800M. Prior to Kabam, Kent was the co-founder and President of Integral Ad Science, the global market leader in digital ad measurement and verification which was acquired by Vista Equity Partners for $850M. Kent is a co- inventor on over 75 patents ranging from streaming technology, virtual reality, location-based mobile applications to video game design. Kent is a prolific industry spokesperson featured in Bloomberg, CNBC, The Wall Street Journal, and Los Angeles Times.
Dr. Brandi Cantarel is a leader in bioinformatics. For over 15 years, she has been involved in projects that utilize sequence technology to understand human health, often on the forefront of an emerging field or technology. She leads bioinformatics development of next-generation sequence (NGS) data, including genomics, transcriptomics and metagenomics in rare/complex genetic diseases, immunology, infectious disease and cancer. She has applied precision medicine research in a CAP/CLIA setting, with the development of tools for tumor mutational profiling. In 2020, Brandi was named a Highly Cited Researcher by Web of Science. Prior, Brandi was a faculty member at the UT Southwestern Medical Center, Department of Bioinformatics and at the University of Maryland, Institute for Genome Sciences.
Brandi has a PhD from the University of Virginia, Department of Biochemistry and Molecular Genetics and a BS in Biochemistry from the University of Maryland, Baltimore County.
Peter Phillips is an accomplished media and technology business leader with a strong track record building high- profile brands and startups. He most recently served as senior advisor to the leadership team at Cameo, a pop culture marketplace, where he helped the business quickly scale past $100M in annual revenue. Prior Peter was Chief Operating Officer at Giphy, the gif database and search engine, where he led all business operations, built the revenue function and co-led fundraising which culminated in a $400M exit to Facebook in 2020. Prior to Giphy he served as EVP and General Manager of Interactive & Distribution at Marvel Entertainment, where he reported directly to the chairman and successfully built and managed its digital media, video games and content distribution divisions. He has also held management roles at Weight Watchers International, Fandango, and Paramount Pictures. Peter often serves as an industry spokesperson and has been interviewed by and quoted in many top industry publications including The Wall Street Journal, USA Today, Fast Company, and Forbes; his accolades include numerous Webby Awards and he is a member of the Academy of Television Arts & Sciences.
Brian Beard is the Chief Legal Officer for Colossal Biosciences Inc. where he helps facilitate strategic company growth and execute on the long-term vision of the company with speed and precision including the various partnerships and licensing.
Over the span of his 35+ year legal career, including 15 years as managing partner of Wilson Sonsini Goodrich Rosati, Brian has served as outside corporate counsel to public and private companies, advising them on a wide range of significant corporate transactions, including mergers and acquisitions, initial public offerings, and private equity and venture capital financings. He has successfully orchestrated and closed thousands of technology transactions as well as hundreds of public offerings for companies and underwriters.
In addition to his legal role, Brian has advised a number of management teams and Boards of Directors on their corporate strategy, with a focus on corporate governance issues.
Sara Ord is Director of Species Restoration at Colossal and is focused on advancing science and technology to change the way we protect endangered species. Sara received her Master’s degree in Chemical and Biomolecular Engineering from Johns Hopkins University where she focused on building integrated materials with chemical information processing mechanisms, inspired by biology. Previously, Sara was a researcher at Hypergiant, where she focused on advancements of chemical and molecular processes in space.
Sara has a Bachelor of Science from California State University, Fullerton where she majored in biological sciences, with a concentration in cellular and developmental biology. Her research has focused on fundamental questions in molecular evolution related to cellular adaptation and response to stress, where she co-authored two papers. Prior, Sara worked at St. David’s Hospital as a pathologist assistant where she gained hands-on experience in the field of histology.
Sara has a passion for science, environmental conservation and the representation of ideas encompassed in these fields. Her work at Colossal aims at the advancement of these ideas through research.
Doug Daniels is Head of Engineering of Colossal. Doug is an engineering leader, with 15+ years software industry experience. Doug has built and led engineering teams that have developed scalable SaaS platforms and services for companies such as Zynga and more recently LivePerson.
Doug has a passion for leveraging software automation and AI to build innovative products and exploring new frontiers at the intersection of science and technology. Doug started his career working at General Dynamics (GC4S) developing network monitoring and simulation technology for the US Airforce and US Army.
Doug has experience building massive scale software platforms at companies such as Zynga pre / post IPO, building million+ daily active user services. Prior to Colossal, Doug was a co-founder at Conversable (acquired by LivePerson) building an enterprise SaaS platform leveraging cutting edge Conversational and AI technologies.
Matt James is a leader in exotic animal care with more than thirteen years of experience in husbandry and welfare. Previously working as the Senior Director of Animal Care for large zoological institutions such as the Dallas Zoo and Zoo Miami, he had the opportunity to manage over 7,000 animals representing more than 500 species, while also maintaining their accreditation standards with the Association of Zoos and Aquariums (AZA).
Firmly believing in a hands-on approach, Matt has managed, cared for, bred, and translocated a large variety of animals including elephants, rhinos, and other mega-vertebrates. Understanding the necessity for collaboration and perpetuating his passion for conservation, he holds several positions within the AZA organization such as serving on the Taxon Advisory Groups for Elephants, Rhinos, and Antelope & Giraffid, and manages the Species Survival Plans for Red River Hogs, Yellow-backed Duikers, and Giraffe.
In addition to acting as an accreditation inspector, he was recently appointed as the Husbandry & Welfare Working Group Chair on the AZA’s Elephant Sustainability Task Force.
Matt has a Bachelors of Science from Doane University where he majored in Biology and Chemistry as well as an MBA from the Muma College of Business at the University of South Florida.
Sarah Grant is a graduate of the University of Texas at Austin. After starting her career in financial services, she joined Chaotic Moon, the leading creative technology studio, which was acquired by Accenture. Shortly after the acquisition, Sarah had a brief stint in public relations but ultimately found herself back in the tech scene at Conversable, the largest AI-powered conversational platform which was later acquired by LivePerson. She was Chief of Staff at Hypergiant, an enterprise AI software company focused on critical infrastructures, space, and defense and remains a Partner. As Chief of Staff at Colossal, she is involved with every aspect of the company as she works side-by-side with the Founder and CEO. She is responsible for managing information flow while prioritizing the CEOs time and appointments, drafting communication, and acts as a sounding board. She handles special projects, press relations, financial transactions and organizes critical issues for the CEO to facilitate efficient decision making and effective leadership. Sarah has supported executives across six companies, eight boards, and two family offices.
At Colossal we're bringing together the greatest minds and leaders in technology, translational medicine, chemical engineering, biotechnology, molecular genetics, and software along with ground breaking entrepreneurs to help guide us on our path. Our team includes practicing physicians, researchers, authors, inventors, professors, and winners of the Anitschkow Prize, National Medal of Technology and Innovation, Breakthrough Prize in Life Sciences and the Harvey Prize.
Professor of Ecology and Evolutionary Biology at UC Santa Cruz and HHMI Investigator
[ COLOSSAL SCIENTIFIC ADVISORY BOARD MEMBER ]
Beth Shapiro is an evolutionary biologist who specializes in the genetics of ice age animals and plants. As Professor of Ecology and Evolutionary Biology at UC Santa Cruz and HHMI Investigator, Beth uses DNA recovered from bones and other remains to study how species evolved through time and how human activities have affected and continue to affect this dynamic process. Her work focuses on organisms ranging from influenza to mammoths, asking
questions about domestication, admixture, speciation, and pathogen evolution. Her current work develops techniques to recover increasingly trace amounts of DNA such as from environmental and forensic samples. A 2009 MacArthur Fellow, Beth is also an award-winning popular science author and communicator who uses her research as a platform to explore the potential of genomic technologies for conservation and medicine.
by Beth Shapiro
When the 2020 Nobel Prize was awarded to the inventors of CRISPR, the revolutionary gene-editing tool, it underlined our amazing and apparently novel powers to alter nature. But as biologist Beth Shapiro argues in Life as We Made It, this phenomenon isn’t new. Humans have been reshaping the world around us for ages, from early dogs to modern bacteria modified to pump out insulin. Indeed, she claims, reshaping nature—resetting the course of evolution, ours and others’—is the essence of what our species does.Learn More +
by Beth Shapiro
Could extinct species, like mammoths and passenger pigeons, be brought back to life? In How to Clone a Mammoth, Beth Shapiro, an evolutionary biologist and pioneer in ancient DNA research, addresses this intriguing question by walking readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used to resurrect the past. Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.Learn More +
We’re also partnering with leaders in critical industry sectors who have deep experience and decades of relationships with Fortune 500 leaders and beyond. This board ensures that we ethically meet our business objectives so our research and development into biosciences can continue to benefit humankind indefinitely.
The ultimate aim of de-extinction and rewilding is to restore delicate, ecosystems back to healthier, more planet-friendly states. Thus it’s critical that we partner with some of the sharpest and most experienced minds in conservation today. For their leadership and advisement, we are forever grateful.
“I’m very excited to invest in Ben and George's new company, Colossal,”
said lead investor Thomas Tull.
“The platform they are building will have a meaningful impact on both ecology and cutting-edge biotechnology.”
We’re proudly partnered with some of the greatest teams and organizations from around the globe. Each equally committed to our vision and shared objectives of restoring the world to a healthier state, de-extinction, preventing, or staving off extinction, and protecting all wildlife in general.
Thomas Tull is founder and CEO of Tulco, a privately held holding company that partners with entrepreneurial companies posed to transform old-line industries using cutting-edge technology. Tull is the founder and former CEO of the well-known film production company Legendary Entertainment
Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness.
At One Ventures finds, funds, and grows teams to catalyze a world where humanity is a net positive to nature.
JAZZ Venture Partners invests in companies that extend the boundaries of human performance — improving how we live, learn, work, play, and experience the world.
The first venture firm with access to 100M+ engaged consumers across the world Driving growth by leveraging proprietary marketing channels and increasing consumer awareness.
GSV supports and partners with exceptional founders and entrepreneurs who push the boundaries of possibility and harness the power of science and technology to build better futures at scale.
Climate Capital invests alongside Tier 1 Seed investors into companies directly or indirectly chipping away at greenhouse gas emissions, or helping with adaptation.
Winklevoss Capital supports determined entrepreneurs by providing guidance, relationships and capital, helping to reinforce their pursuit of a frictionless world and a better human experience.
Breyer Capital is a premier global venture capital and private equity fund focused on catalyzing high-impact entrepreneurs in the United States and China.
Untamed Planet is on a mission to protect the wild by building a metaverse for mother nature.
Animoca Brands is driving digital property rights via NFTs and gaming to build the open metaverse.
BOLD is a venture capital firm that seeks entrepreneurs and companies who share a fierce vision for a brighter tomorrow.
Boost VC is an early stage VC firm in San Mateo, CA founded by Adam Draper & Brayton Williams. They invest in pre-seed startups accelerating the Sci-Fi Future (aerospace, energy, climate, robotics, crypto, biotech, virtual reality & more).
Conserve & Protect :
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in three locations that include laboratories, test facilities, academic institutions, libraries and offices.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.