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Immortalized in Game of Thrones and on the crest of House Stark, the dire wolf is walking the Earth again and even howling after going extinct nearly 10,000 years ago.
As announced today by genetic engineering company Colossal Biosciences, the long-extinct canine — or at least a very close approximation of it — has been successfully brought back to life. The process was accomplished via DNA extracted from two fossils as well as 20 edits of the genetic code of a gray wolf, the species’ closest living relative, according to research carried out by Colossal, sometimes known as the De-Extinction Company.
Colossal says it has whelped three dire wolves and — using CRISPR technology — decided to select fluffy white fur for their coats, based on its new analysis that the original species had snow-colored fur. (A previous study, published in Nature in 2021, found evidence that dire wolves were not closely related to gray wolves.)
The Colossal company has named its two new male dire wolves — a pair of six-month old adolescents — Romulus and Remus, after the mythological twin founders of Rome, who were said to have been raised by a wolf. And in an homage to Game of Thrones’ Daenerys Targaryen, it’s christened a female puppy Khaleesi.
The trio are now living in an enclosed preserve of more than 2,000 acres at an undisclosed location. They are expected to mature at 130 to 150 pounds — by contrast, a typical gray wolf clocks in at about 80 to 100 pounds.
“Our team took DNA from a 13,000-year-old tooth and a 72,000-year-old skull and made healthy dire wolf puppies,” says Colossal CEO and co-founder Ben Lamm in a statement. “It was once said, ‘any sufficiently advanced technology is indistinguishable from magic.’ Today, our team gets to unveil some of the magic they are working on and its broader impact on conservation.”
In a twist that could only have been dreamed up by Hollywood, filmmaker Peter Jackson and Game of Thrones creator George R.R. Martin collaborated with Colossal Biosciences on today’s reveal of what the company is trumpeting as the first-ever de-extinction of an animal.
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