In this GamesBeat feature, Colossal Biosciences reveals the birth of genetically engineered pups modeled on the extinct dire wolf. Using ancient DNA from fossils, the team introduced around 20 targeted gene edits to replicate physical traits—not the species itself. The pups—named Romulus, Remus, and Khaleesi—were born via surrogate dogs and housed in a secure preserve. While hailed as a first in de‑extinction, the work has drawn debate from scientists who question whether editing a few genes can equate to reviving an extinct species. Colossal positions the dire wolf project as a platform for advancing genomics and conservation bioscience, rather than reviving historical species outright.
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