The Science of De-Extinction: Inside Colossal’s Mission to Revive the Past for the Future

From woolly mammoths to ecological restoration, Colossal’s co-founders break down how science is reshaping conservation.

In this in-depth interview with CBR, Colossal Biosciences co-founders Ben Lamm and George Church clarify what de-extinction really is—and what it isn’t. Rather than recreating dinosaurs or chasing spectacle, Colossal’s mission is rooted in cutting-edge genetics and a deep commitment to conservation. The article explores how species like the woolly mammoth, thylacine, and dodo could be reintroduced as ecological stand-ins to help restore balance to endangered ecosystems. Lamm and Church emphasize transparency, scientific rigor, and the ethical frameworks that guide the work. They also discuss how CRISPR, cell preservation, and advanced breeding techniques are being used in tandem to move the field forward. This piece offers a thoughtful look at how Colossal is combining ambition with responsibility to help build a more biodiverse future.

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