Dire Wolves Return from Extinction: How Ancient DNA Is Bringing the Game of Thrones-Famous Puppies Back to Life

"Today, our team gets to unveil some of the magic they are working on and its broader impact on conservation," Colossal Biosciences' CEO said in a statement

BY Adam Carlson

In an announcement straight out of ancient history — or the pages of a George R. R. Martin novel — a leading genetics company says it has essentially revived the extinct dire wolves that famously appeared in Game of Thrones.

Meet Romulus, Remus and, yes, Khalessi: three young dire wolves being raised in an undisclosed nature preserve that Colossal Biosciences describes as carrying the traits of the long-lost giant canines.

Their successful creation, which had been a closely guarded secret until this week, is the next step in what Colossal has termed its de-extinction project.

The company uses gene editing to modify the traits of existing animals to the point that their DNA becomes, essentially, that of lost animals.

“Our team took DNA from a 13,000-year-old tooth and a 72,000-year-old skull and made healthy dire wolf puppies,” Colossal CEO and co-founder Ben Lamm said in a statement on Monday, April 7.

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