Dire Wolves Reborn? Behind Colossal’s Bold Science

People Magazine explores Colossal’s work in engineering canids with traits inspired by the extinct dire wolf.

BY Adam Carlson

In this People article, the public-facing side of Colossal’s dire wolf effort takes center stage. The story details the birth of gene-edited canid pups—Romulus, Remus, and Khaleesi—engineered to exhibit traits inspired by the extinct dire wolf. Colossal scientists applied CRISPR-based edits targeting dozens of genetic loci believed to influence key physical characteristics. The feature weaves together science and broader cultural resonance, raising important ethical and scientific questions about functional de-extinction and whether projecting extinct traits into living animals crosses the line between innovation and imitation.

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