Inside Colossal’s Dire Wolf De‑Extinction: Myth, Media & Modern Science

Complex sits down with Colossal to explore how the company blends ancient lore and cutting‑edge genetics to reimagine the dire wolf for today.

BY Brighid Tully

In this feature by Complex, the spotlight is on Brighid Tully and the Colossal Biosciences team as they navigate the intersection of cultural mythology and advanced genetics in reviving the dire wolf. The piece explores how the project draws inspiration from ancient legends while leveraging tools like CRISPR, stem‑cell tech, and synthetic biology to engineer a new canid lineage with dire wolf characteristics. Tully delves into the storytelling behind the science, discussing how public fascination shapes and informs the research. The article balances the narrative’s mythical elements with the rigorous scientific process behind gene-editing and reproductive platforms. Ultimately, it paints a portrait of a project that is as much about human storytelling and cultural memory as it is about biotechnology and biodiversity.

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